Most recent job postings at ngs
via LinkedIn posted_at: 18 hours agoschedule_type: Full-timework_from_home: 1
Business Development Director/Manager - Synthetic Biology / NGS (Next-generation Sequencing) REMOTE - USA... • *NO VISA SPONSORSHIP** Frequent Travel This is an opportunity to join a leading provider of genomics and proteomics services in the Americas Region who are looking for a passionate business development executive experienced in the synthetic biology industry to lead global expansion in the genomics engineering field. Your main responsibilities Business Development Director/Manager - Synthetic Biology / NGS (Next-generation Sequencing)

REMOTE - USA...
• *NO VISA SPONSORSHIP**

Frequent Travel

This is an opportunity to join a leading provider of genomics and proteomics services in the Americas Region who are looking for a passionate business development executive experienced in the synthetic biology industry to lead global expansion in the genomics engineering field.

Your main responsibilities will include collaborating with global product, marketing, and technical teams to perform a thorough competitive analysis of Company’s synthetic biology product solutions and market opportunities and defining business strategies, tactics, and roadmap to grow synthetic biology business in global markets.

Job Requirements:
• B.S. degree in biology, molecular biology, genomics, bioinformatics, or equivalent majors. Advanced degrees preferred.
• Requires a minimal of 3-5 years technical experience in the synthetic biology area.
• Working knowledge of genomics, next-generation sequencing (NGS) & gene editing preferred.
• 3-5 years commercial experience in sales, business development, marketing, product management in the related industry preferred.
• Willingness to accept 50% travel
• Requires American citizenship or working authorization in the U.S.

For more information, please apply via LinkedIn or send your CV to aw@eu-recruit.com.

Keywords:

Business Development / Sales / Marketing / Product Management / Genomics / Gene Editing / Synthetic Biology / Biology / Next-Generation Sequencing (NGS) /

By applying to this role you understand that we may collect your personal data, store and process it on our systems. For more information please see our Privacy Notice.

(https://eu-recruit.com/about-us/privacy-notice/)

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via AstraZeneca Careers posted_at: 3 days agoschedule_type: Full-time
AstraZeneca has an opening for a Senior Scientist within the Biologics Engineering Department to support pre-Clinical research of innovative therapeutic products. Expertise in state-of-the-art molecular biology and next-generation sequencing techniques is critical. At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial... thinking big and working together to make the impossible AstraZeneca has an opening for a Senior Scientist within the Biologics Engineering Department to support pre-Clinical research of innovative therapeutic products. Expertise in state-of-the-art molecular biology and next-generation sequencing techniques is critical.

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial... thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and on-site day care. This is where you’ll find activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

The Protein Science group is at the heart of the Biologics Engineering department. We provide custom reagents in support of all therapeutic areas. We are a science-led expert function of people with curious minds that supports the discovery and engineering of novel biomolecules. We are passionate about collaboration and developing cutting edge technologies to create the next generation of biotherapeutics to improve patients’ lives.

What you’ll do
We are seeking candidates with a Ph.D. degree in Biochemical/Biomedical Engineering, Biotechnology, Biological Sciences or related field with 0-3 years of experience performing next-generation sequencing and data analysis. You will support sequencing projects for multiple pre-clinical programs in Cancer, Inflammation, Cardiovascular, Metabolic Disease and Infectious Disease. Extensive hand-on experiences with NGS library prep, sample/library QC and instruments such as Illumina/PacBio/Nanopore is required. Your ability to multi-task and quickly adjust to changes in priorities and timelines will be critical. Knowledge of bioinformatics analysis is highly preferred.

Essential for the role
• Ph.D. Degree with 0-3 years of experience performing next-generation sequencing and data analysis
• Proficiency in NGS library prep, sample/library QC and instruments is required.
• Ability to multi-task and quickly adjust to changes in priorities and timelines will be critical.
• Good communication and documentation skills are essential.
• Desirable for the role
• Knowledge of bioinformatics analysis is highly preferred.
• Experience with single cell sequencing.

Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential.

Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next!
• Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law
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via LinkedIn posted_at: 1 day agoschedule_type: Full-timesalary: 25–32 an hour
Position: Lab Technologist I- NGS Client: Healthcare Client... Location: Columbus, Ohio Duration: 6 month contract to hire Responsibilities: • Perform a variety of tests in clinical laboratories using standard techniques and equipment • Perform related duties in the laboratory to include specimen handling, using manual and automatic equipment to test specimens, and perform and report analytical tests • Demonstrates proficiency in operation, Position: Lab Technologist I- NGS

Client: Healthcare Client...

Location: Columbus, Ohio

Duration: 6 month contract to hire

Responsibilities:
• Perform a variety of tests in clinical laboratories using standard techniques and equipment
• Perform related duties in the laboratory to include specimen handling, using manual and automatic equipment to test specimens, and perform and report analytical tests
• Demonstrates proficiency in operation, cleaning and maintenance of laboratory instrumentation
• Reviews completed cases and summarizes the results for clinical reports and/or research studies
• Demonstrates an ability to accurately record procedures in laboratory notebooks
• Performs secondary technical review of cases prior to sign-out
• Prepares written results of research and development activities and oral reports when appropriate; utilizes chart, graphs, tables as needed
• Hours of this position will be Monday through Friday, 8:30am to 5pm

Qualifications:
• Bachelor’s degree required
• 1 year of Lab Experience
• Attention to Detail
• Ability to work well with other
• Ability to understand and describe technical aspects of Molecular testing or NGS

What’s In It For You:
• Opportunity to be on front lines using cutting edge technology advances in genome sequencing to help diagnose and treat kids with cancer and other rare genetic diseases.
• Work with internationally renowned genomic medicine scientists, in the campus’ newest research building, spanning ~25,000 square feet of laboratory and office space in a highly interactive setting.
• Support a team implementing new testing methods
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via Salary.com posted_at: 2 days agoschedule_type: Full-time
Agilent inspires and supports discoveries that advance quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek -- so they can do what they do best: improve the world around us. Information about Agilent is available at... www.agilent.com. Reporting to the Vice President of Agilent inspires and supports discoveries that advance quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek -- so they can do what they do best: improve the world around us. Information about Agilent is available at... www.agilent.com.

Reporting to the Vice President of Global Regulatory Affairs, the Director of Regulatory Affairs, Next Generation Sequencing (NGS) Companion Diagnostics (CDx) is responsible for establishing the regulatory strategy for Agilent's NGS CDx business.

This position will partner with Global Quality and Regulatory Affairs colleagues and Agilent's NGS CDx leadership team to establish regulatory strategies and provide input to liquid biopsy and Companion Diagnostic businesses, support liquid biopsy projects and business objectives, play a significant role in establishing and maintaining relationships with pharma partners, ensure regulatory submissions for all new products and modifications to existing products, and partner on the execution of regulatory responsibilities, in accordance with global regulatory policy and processes.

The Director of Regulatory Affairs, NGS CDx will manage a team of direct reports and will periodically travel to support business objectives. Key responsibilities include:
• Working with other functional leads on the strategic planning for the Agilent's liquid biopsy NGS business.
• Serving as a leader in the Global Regulatory Affairs organization, supporting the overall Global Regulatory Affairs strategic initiatives and collaborating across Agilent divisions.
• Actively managing departmental budget to meet strategic goals.
• Working closely with Agilent NGS CDx functional heads in establishing and implementing business and strategic goals.
• Developing and implementing liquid biopsy NGS and Companion Diagnostic regulatory strategies in alignment with business needs.
• Collaborating with pharmaceutical partners in drug and diagnostic co-development programs.
• Ensuring the accurate and timely preparation of regulatory submissions and reporting in accordance with company goals, regulatory requirements, and partnership contracts.
• Leading interactions with the US FDA and other regulatory agencies in support of initial device approvals and device modifications.
• Leading reviews of product labelling and advertising/promotional materials.
• Participating in Joint Steering Committees and Joint Project Teams with pharm partners as the senior representative of Global Regulatory Affairs within Agilent's NGS CDx business.
• Establishing active dialogues with global health authorities, customers, distributors, pharma partners, and colleagues globally.
• Preparing and presenting project status reports, strategies, and initiatives to business, regulatory, and leadership teams.
• Working across Agilent in formulating regulatory processes/procedures and sharing best practices/knowledge with regulatory colleagues.
• Staying abreast of global IVD regulations and guidance, especially those relevant to NGS, liquid biopsy, and Companion Diagnostics. Influences new regulatory policy as science and technology advances.
• Managing and developing regulatory talent within the Agilent NGS CDx Regulatory Affairs team and more broadly within the Global Regulatory Affairs organization and Agilent overall.

Qualifications

Education:
• Bachelors or master's degree or University Degree or equivalent in a related field, preferred biological or molecular sciences.
• Advanced degree or regulatory affairs certification preferred, directly relevant experience as a manager, supervisor preferred.

Experience:
• Minimum of (8 ) years of Regulatory Affairs leadership roles of increasing responsibility in in vitro diagnostics.
• Experience in liquid biopsy NGS and Companion Diagnostics.
• Has led company-sponsored interactions with regulatory bodies, especially US FDA and EU Notified Bodies.
• Experience with worldwide regulatory submissions and approvals with respect to in vitro diagnostic devices (IVDs), including class III (PMA) submission to US FDA.
• Direct experience with national and international regulatory registrations and demonstrated ability to develop effective relationships with regulatory agency representatives.
• Demonstrated track record of results using interpersonal, relationship-building skills required to lead multi-cultural and geographically dispersed teams in a fast-paced, highly matrixed environment.
• Experience in engaging pharma partners in Companion Diagnostic collaborations.

Personal Characteristics
• Transformational leader who brings intensity & excitement every day.
• Passionate, visionary thinker with a desire to excel and inspire others.
• High degree of self-awareness and emotional intelligence.
• Creative thinker willing to explore unique, out-of-the-box solutions.
• Ability to weave complex concepts into a clear compelling message.
• Excellent collaboration, influencing and facilitation skills across business groups, functions and employee levels.
• Pragmatic and customer focused.
• Ability to identify and focus on key priorities.
• Self-starter, self-reliant, courage of conviction.
• Willingness to engage teams and business partners across multiple time zones.

The US pay range for this full-time position is $143,760.00 - $265,058.00/yr, plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum new hire pay for the position across the relevant US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Additional details are available at: https://careers.agilent.com/locations/americas/united-states/

Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email job_posting@agilent.com or contact 1-262-754-5030.

For more information about equal employment opportunity protections, please see all of our notices for EEO below.

Pay Range

$143,760.00-$265,058.00

The salary range for this position may differ based on your actual work location.

Eligible for Company Car

No

Benefits in Brief

Option to Work Remote

Yes

Travel Required

Occasional

Schedule

Schedule:Full time

Shift

Day

Duration

No End Date

Job Function

Quality/Regulatory
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via Roche Careers posted_at: 25 days agoschedule_type: Full-time
The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to support the algorithm development... efforts. In this role, you will collaborate closely The Position

Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist in the NGS Algorithms and Applications team to support the algorithm development... efforts.

In this role, you will collaborate closely with molecular biologists, software engineers and other bioinformatics scientist and apply your strong knowledge in next generation sequencing technologies. This will include illumine SBS (sequencing by synthesis), nanopore, etc. to design and develop algorithms for read processing, alignment, and variant (SNV, insertions/deletions, CNV, TMB, MSI) callers etc. This will be used in our products that will affect patient care.

Responsibilities:
• Lead and partner closely with molecular biology, engineering, and other bioinformatics teams to perform all aspects of algorithm development including algorithm design, experimental design, performance evaluation, QC, documentation, visualization and communication of results
• Follow software development process and deliver and maintain documentation that explains why and how as well as the final design for scientific, marketing, and regulatory uses
• Present and communicate updates across multiple functions in the organization. Transfer algorithm to production teams and provide scientific support for updates and maintenance
• Support bioinformatics pipeline to continue development for existing products

Qualifications:
• PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Mathematics or other quantitative field combined with 5+ years’ experience of designing novel algorithms for NGS data analysis for example read processing, variant calling (SNV, insertions/deletions, CNV, TMB, MSI etc.), variant annotation and analyzing large scale complex genomic datasets
• Experiences in design and evaluation statistical and mathematical method and able to implement with efficient resource use and high-quality code
• In depth knowledge of sequencing molecular biology, bioinformatics tools, statistical methods, and cancer biology.• Proficient with programming languages (Python preferred, or R and Java) in a distributed Linux environment
• Hands-on experience using a workflow management system such as Nextflow or Snakemake, using Docker and cloud computation resource and storage
• Strong written and verbal communication skills with ability to adjust to technical and non-technical audiences
• Result-oriented individual that thrives in collaborative multi-disciplinary teams. Excels at incorporating feedback in a professional manner

Compensation Range:
• The expected salary range for this position based on the primary location of Pleasanton CA is $142,100 - $263,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation assistance is not available for this role.

#LI-SC3

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company’s health and safety obligations and/or applicable law or guidelines.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com
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via Danaher Jobs posted_at: 16 days agoschedule_type: Full-time
Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications. Our work is complex and cutting-edge, and our team members are curious, creative thinkers who understand that good data drives smart decisions. At IDT, we realize that although science may be uniform, people are unique. We promote a diverse and inclusive... culture where engaged people are motivated to share Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications. Our work is complex and cutting-edge, and our team members are curious, creative thinkers who understand that good data drives smart decisions. At IDT, we realize that although science may be uniform, people are unique. We promote a diverse and inclusive... culture where engaged people are motivated to share their ideas and have opportunities to achieve their full potential, as part of one global team.

IDT is one of 10 Life Sciences companies of Danaher. Together, we accelerate the discovery, development and delivery of solutions that safeguard and improve human health.

Job Title: NGS Technical Sales Representative

Territory: Midwest (IL, MN, Dakotas, WI, MI, IA, NE)

Location: Remote

We believe in designing a better, more sustainable workforce. We recognize the benefits of flexible, remote working arrangements for eligible roles and are committed to providing enriching careers regardless of your geographic location. This position is eligible to work remotely from your home. Additional information will be provided by your interview team. Explore the flexibility, challenge, and reward that working here can provide.

Purpose statement:

The Technical Sales Representative is responsible for leading the promotion and sales of IDT’s Archer AMP™ solutions in the field of oncology somatic and germline testing. This role requires strategic and consistent delivery of customer support and satisfaction, while managing and driving customer consultation and partnership to achieve profit and revenue growth goals within the assigned territory.

Essential Functions:
• Develops and manages assigned accounts to deliver solutions and drive revenue growth
• Researches and understands territory dynamics focusing on prospecting and growth opportunities to develop an effective business plan and sales strategy
• Maintains and develops strategic partnerships with key customers and leverages internal resources, when necessary, to achieve the highest level of customer satisfaction
• Develops the client relationship by understanding both short and long-term needs/goals for optimal positioning of Archer products and software.
• Schedules sales calls and travel itinerary to address customer needs and executes sales strategies through timely follow up, including detailed notes captured within current CRM tools.
• Builds in-depth knowledge of CRM and funnel management tools and applies these skills consistently to forecast business, manage customer opportunities, build opportunity pipeline, and make business decisions. Maintains records and communications with customer base with current CRM tools.
• Maintains regular and informative communications with all other team members, including cross-functional collaboration with Product Managers, Application Scientists, Inside Sales, etc.
• Educates and provides customers with current product sales information through technical presentations.
• Understands the competitive landscape and evaluates competitor’s products to s effectively position Archer solutions for a successful sale.
• Participates in exhibitions and provides quantitative and qualitative feedback on events attended.
• Strictly adheres to all company compliance policies and demonstrates behavior consistent with the Integrated DNA Technologies and Danaher Core Values.
• Performs other duties as assigned.

Education:
• Bachelor's degree in a relevant Life Science sales experience required or an advanced degree in a Life Science field preferred. Valid driver’s license required.

Professional Experience:
• Five years of prior molecular and/or laboratory pathology sales experience required; preferably in molecular biology reagents/laboratory consumables/capital equipment.
• Proven track record of meeting or exceeding sales targets for at least 3 years is required.
• Residing in the assigned region and extensive familiarity with existing academic, National Comprehensive Cancer Network (NCCN), corporate, and government accounts in the region is required.
• Applications experience within NGS, qPCR, molecular profiling, etc. and working knowledge of accounts in assigned territory is preferred.

Other Job Qualifications
• Ability to develop and implement strategic and tactical plans to achieve defined goals.
• Ability to make decisions in a changing environment and anticipate future needs.
• Exceptional written, oral, interpersonal and presentation skills. Ability to effectively communicate with various stakeholders involved in decision making.
• Proven track record of driving profitable revenue and market share growth, demonstrated over a sustained period.
• Adaptability to perform a variety of duties, often changing from one task to another without loss of efficiency or composure.
• Outstanding prospecting, territory management, lead management, negotiation, and closing skills.

Travel Requirements (anything requiring overnight stay):
• Around 25-50% in the assigned territory

What We Offer:
• Shift Differentials (Extra Compensation for less traditional shifts)
• Generous Paid Time Off Accruals
• 16 Hours PAID Volunteer Time Off
• 11 Paid Holidays
• Up to eight (8) weeks of 100% paid parental leave to eligible U.S. associates
• 401(k) with Company Match
• Medical, Dental, and Vision Insurance Options

Integrated DNA Technologies (IDT) conducts drug screens and background checks on applicants who accept employment offers.

The salary range for this role is $93,000-130,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.

This job is also eligible for bonus/incentive pay.

We offer a comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.

When you join us, you’ll also be joining Danaher’s global organization, where 80,000 people wake up every day determined to help our customers win. As an associate, you’ll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System (https://www.danaher.com/how-we-work/danaher-business-system) tools and the stability of a tested organization.

Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.The EEO posters are available here (https://www.dol.gov/agencies/ofccp/posters) .We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation. If you’ve ever wondered what’s within you, there’s no better time to find out
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via Lever posted_at: 9 days agoschedule_type: Full-time
At Arbor, we envision a world free of disease by using genetic medicines to fundamentally shift the paradigm from treatment to functional cure and ultimately to prevention. We aim to accomplish this through the discovery of programmable DNA editors with the power to enable bespoke curative genetic medicines for patients. What You Will Do... We are searching for a Research Associate to assist with the daily operation of our automated, high-throughput At Arbor, we envision a world free of disease by using genetic medicines to fundamentally shift the paradigm from treatment to functional cure and ultimately to prevention. We aim to accomplish this through the discovery of programmable DNA editors with the power to enable bespoke curative genetic medicines for patients.

What You Will Do...

We are searching for a Research Associate to assist with the daily operation of our automated, high-throughput Next Generation Sequencing (NGS) process. The Core Services team serves Arbor’s various programs and scientists developing cutting-edge CRISPR technologies and therapeutics. An ideal candidate for this position should demonstrate the ability to work both independently as well as collaborate with the team. They should be detail-oriented, demonstrate strong problem-solving and troubleshooting skills, and contribute to the continuous improvement of the lab and informatic processes related to NGS.

Responsibilities:
• Perform daily NGS prep tasks according to Standard Operating Procedures
• Interface with automated hardware, including high-throughput liquid handlers and robotics, to perform these tasks
• Analyze, interpret, and present NGS data and help develop new metrics to monitor data quality
• Troubleshoot issues and provide feedback to improve the NGS process
• Train and communicate the process to new users of the workflow

Qualifications:
• Bachelor’s degree in biology, bio-engineering, or biochemistry and 0-2 years of experience with molecular biology techniques, including DNA purification, PCR, NGS and NGS library preparation, DNA and RNA quantification, gel extraction, library construction, and cloning
• Hands-on experiences with lab automation and liquid handlers, such as the HighRes Prime, Echo, and Bravo systems
• Strong documentation, communication, time management, prioritization, and problem-solving skills
• Ability to work in a dynamic, fast-paced environment
• Experience with Microsoft Office Suite

Added Value:
• Familiarity with Laboratory Information Management Systems (LIMS) such as Benchling
• Familiarity with programming and query languages, such as Python and SQL

Our Values:

Our values govern the work we do at Arbor, and we’re hoping that they resonate as strongly with you as they do with us!

· Purposeful Action: Start with The Why

· Bold Resilience: Adopt a Growth Mindset

· Humble Authenticity: Start in the Heart

About Arbor:

At Arbor, we are discovering, developing and making available to all patients the next-generation of genetic medicines. We are disrupting the field through our proprietary discovery engine to develop a portfolio of differentiated genetic editing and delivery capabilities. We have an unencumbered portfolio of multiple CRISPR based genetic modifiers that can be tailored to correct the underlying pathology of each genetic disease. Our pipeline of genetic medicines will focus on bringing cures to all patients with genetic disease.

We seek highly-motivated individuals with the dedication, integrity, and creative spirit needed to thrive in an innovative company. Working at Arbor offers a unique opportunity that combines the fast pace and growth opportunities of a startup with the intellectual rigor and creativity of academia. Our salaries are competitive, our benefits are generous, and our team is exceptional.

We promote diversity and inclusion not just in our recruitment processes, but in everything we do. We’re an equal opportunity employer and we will continue to ensure our recruitment process is free of bias and our workplace is inclusive, positive, and free of discrimination and respecting of all backgrounds and beliefs
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via MD Anderson - MD Anderson Cancer Center posted_at: 22 days agoschedule_type: Full-time
SUMMARY The Genetics Department is a basic science department located in the George and Cynthia Mitchell Basic Sciences Research Building at the world-renowned University of Texas MD Anderson Cancer Center in the heart of the Texas Medical Center. The focus is on advancing knowledge of the molecular genetic mechanisms that regulate normal and abnormal cellular processes... The University of Texas MD Anderson Cancer Center in Houston is one of the SUMMARY

The Genetics Department is a basic science department located in the George and Cynthia Mitchell Basic Sciences Research Building at the world-renowned University of Texas MD Anderson Cancer Center in the heart of the Texas Medical Center. The focus is on advancing knowledge of the molecular genetic mechanisms that regulate normal and abnormal cellular processes...

The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2018 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer Institute.

The primary purpose of the Associate Data Scientist position is to provide bioinformatics analysis of next generation sequencing (NGS) data for faculty across the institution, to process NGS data for Advanced Technology Genomics Core facility, to perform quality control (QC) analysis and to maintain QC metrics and sample records of NGS experiments on the servers, and to meet with faculty to review data analysis results. This position impacts cancer research projects by developing/maintaining programs and applications tailored to meet research objectives and makes them available to the wider cancer research community.

The ideal candidate will have working experience in analyzing genomic and epigenomic data. Experience in NGS data analysis (expression profiling, mutations and structural variations, and differential peak analysis), data integration, and data mining. Proficiency in at least one programming language such as R, Python, or PERL.

KEY FUNCTIONS
• Performs bioinformatics analysis of bulk RNA-Seq and scRNA-Seq datasets in terms of gene expression profiling analysis.
• Performs bioinformatics analysis of DNA-Seq and scDNA-Seq in terms of detection of both mutations and structural variations.
• Performs bioinformatics analysis of ChIP-Seq, ATAC-Seq, and scATAC-Seq datasets in terms of genome wide profiling of histone modifications and chromosome accessibility.
• Develop software pipelines to perform standard NGS data analysis routine in an automated fashion.
• Perform quality control (QC) analysis on NGS data, and maintain QC metrics and sample records of NGS experiments on the servers.
• Work with bioinformatics faculty, IT personnel, and other researchers to respond to new technologies.

Other Skills
• Expertise in programming languages such as Python, PERL, or R.
• Expertise in linux/unix based environments.
• Excellent communication skills and team-working attitude will be essential.
• Other duties as assigned.

EDUCATION

Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field.

EXPERIENCE

Required: Two years experience in scientific software development/analysis.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

Additional Information
• Requisition ID: 157084
• Employment Status: Full-Time
• Employee Status: Regular
• Work Week: Days
• Minimum Salary: US Dollar (USD) 71,000
• Midpoint Salary: US Dollar (USD) 89,000
• Maximum Salary : US Dollar (USD) 107,000
• FLSA: exempt and not eligible for overtime pay
• Fund Type: Soft
• Work Location: Onsite
• Pivotal Position: Yes
• Referral Bonus Available?: No
• Relocation Assistance Available?: Yes
• Science Jobs: Yes
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via Salary.com posted_at: 1 day agoschedule_type: Full-time
Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments... for the right patients, at the right time. Responsibilities: • Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments... for the right patients, at the right time.

Responsibilities:
• Lead a team of Scientist and BI analysts to develop custom workflows for sample preparation, NGS, and proteomic applications
• Establish scientific approach and work statements for each project to meet the client objectives and expected outcomes
• Manage the service of client facing projects to include but not limited to:
• Initial discovery studies for solutions to challenging samples or study parameters
• Custom RUO NGS workflow development
• Integration of new/bespoke processes into automation workflows and SOPs
• Execution of project specific pilot studies
• Provide flexible support for other activities in Tempus-wide R&D and clinical NGS labs including troubleshooting, emerging technology assessment, etc.
• Mentor and direct scientific laboratory staff

Qualifications:
• Previous molecular assay development and validation experience
• Expertise in nucleic acid isolation from various biospecimen types
• Expertise in various NGS library preparation methods
• Highly organized and systematic, superb attention to detail and ability to complete tasks with a high degree of accuracy
• Experience managing a team and collaborating with cross-functional groups
• Ability to learn new skills quickly and adapt to new processes smoothly
• Ph.D. and 5 years experience in molecular assay development required

#LI-GL1

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status
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via Leidosbiomed.csod.com posted_at: 17 days agoschedule_type: Full-time
Research Associate I/II - NGS Job ID: req3413... Employee Type: exempt full-time Division: Clinical Research Program Facility: Frederick: Ft Detrick Location: PO Box B, Frederick, MD 21702 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems Research Associate I/II - NGS

Job ID: req3413...
Employee Type: exempt full-time
Division: Clinical Research Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM
DESCRIPTION

The Molecular Characterization
Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research
Directorate (CRD) at the Frederick National Laboratory for Cancer Research. Our
laboratory consists of a dynamic team of over 40 scientific, informatics and
support staff. For over 10 years, MoCha has worked closely with the
National Cancer Institute’s Division of Cancer Treatment and Diagnosis (DCTD)
in support of DCTD-sponsored clinical trials and pre-clinical studies. We are
dedicated to implementing cutting-edge genomic technologies to identify new
predictive biomarkers and to make translational discoveries that will improve
the lives of patients with cancer. The Molecular Characterization
Laboratory (MoCha) focuses on development and application of novel genomic
assays for clinical applications
• **This position can be hired at either the Research Associate I or II level.

KEY
ROLES/RESPONSIBILITIES

The
Research Associate I/II will perform nucleic acid extractions, single cell
genomics, spatial transcriptomics, ctDNA and other next generation sequencing
(NGS) assays both manually and using automated platforms to facilitate cutting
edge genomic research in support of DCTD projects, e.g., MDNET clinical trials,
NCI-MATCH correlative studies, and genomic characterization of patient samples
enrolled in ETCTN/NCLN clinical trials.
• Performs nucleic acid extractions, single cell genomics,
spatial transcriptomics, ctDNA and other NGS assays
• Performs next generation sequencing assays following
detailed SOPs, in both research and regulated settings
• Makes detailed observations, follows thorough and timely
recordkeeping processes, analyzes data and interprets results
• Exercises independent judgment in developing and/or
modifying methods and techniques for solving scientific problems
• Maintains essential laboratory supplies and monitors
equipment for optimum performance
• Investigates, creates and develops new methods and
technologies for project advancement utilizing sound scientific judgement
• Writes SOPs and performs formal reporting of research data,
including presentations and/or scientific publications
• Will be key staff member for above-mentioned activities
• Maintains high level of professional expertise through
familiarity with scientific literature and presentations
• May participate in scientific conferences and contribute to
scientific journals
• May be responsible for identifying patentable inventions
• This position
will be located in Frederick, Maryland

BASIC
QUALIFICATIONS

To be
considered for this position, you must minimally meet the knowledge, skills,
and abilities listed below:
• Possession
of a Bachelor’s degree from an accredited college/university according to the
Council for Higher Education Accreditation (CHEA) or four (4) years of
experience in lieu of degree
• Foreign degrees must be evaluated for U.S. equivalency
• Research
Associate I - In addition to the education
requirement, a minimum of two (2) years of progressively responsible
experience
• Research
Associate II- In
addition to the education requirement, a minimum of five (5) years of
progressively responsible experience
• Ability to track information in a large cohort of samples
and monitor progress of multiple projects
• Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
• Strong technical skills in molecular assays and/or nucleic acid extraction and understanding of QC metrics of nucleic acids
• Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
• Strong technical skills in molecular assays and/or nucleic acid extraction and understanding of QC metrics of nucleic acids
• Adequate computer skills to document, organize, and present
experimental data
• Strong critical thinking and problem solving skills
• Ability to communicate effectively, both verbally and in
writing
• Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:
• Experience
working in a CLIA, CAP, GLP, or ISO accredited laboratory
• Experience
in NGS genomic profiling assays
• Experience
in genomic assay development and workflow automation
• Familiarity
with clinical oncology studies and other protocol-driven clinical research

EXPECTED COMPETENCIES
• Proficient with Microsoft Office programs (Word, Excel,
Powerpoint, Access)
• Excellent communication skills (written and oral)
• Strong technical skills in molecular biological and genomic
assays

JOB HAZARDS
• This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

#readytowork
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